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Computational Immunologist

10X Genomics

This is a Full-time position in Anaheim, CA posted September 13, 2021.

At 10x Genomics, accelerating our understanding of biology is more than a mission for us.

It is a commitment.

This is the century of biology, and the breakthroughs we make now have the potential to change the world.

We enable scientists to advance their research, allowing them to address scientific questions they did not even know they could ask.

Our tools have enabled fundamental discoveries across biology including cancer, immunology, and neuroscience.

Our teams are empowered and encouraged to follow their passions, pursue new ideas, and perform at their best in an inclusive and dynamic environment.

We know that behind every scientific breakthrough, there is a deep infrastructure of talented people driving the life sciences industry and making it possible for scientists and clinicians to make new strides.

We are dedicated to finding the very best person for every aspect of our work because the innovations and discoveries that we enable together will lead to better technologies, better treatments, and a better future.

Find out how you can make a 10x difference.

We are looking for an outstanding individual to join our Computational Biology group.

You will work at the intersection of Computational Biology and Immunology to perform analyses and develop methods to drive forwards our understanding of immunological processes at unprecedented scale and resolution.

You will work closely with talented and highly motivated biochemists, microfluidics engineers, chemists and software engineers as we continue to develop our immunology-focused products and use them in exciting and novel ways.

About the role: Your work will involve questions in the areas of antigen receptor repertoires and specificities whilst also covering other areas of immunological research.You will develop new methods to analyze and interpret Next Generation Sequencing (NGS) data from our assays.

You will also apply these methods to datasets that we generate ourselves or with collaborators.

You will provide input into the development of the next generation of Immunology solutions at 10x.

You have a deep background in adaptive immunology and immune repertoires alongside strong computational and analytical skills.

You are a good programmer who can take an idea and quickly implement it in code.

You understand the complexities inherent in immune repertoires and enjoy the challenge of addressing them.

You know how to design an analytical approach to get the best from a dataset.

You are able to communicate your ideas and work effectively with an interdisciplinary team and incorporate their feedback into your analysis.

You are a strategic thinker, highly motivated, action driven and flexible in changing direction and methods.

You thrive in a fast paced environment, excel at managing multiple priorities, communicate clearly and get the job done.

What you will be doing: Develop computational methods for the analysis of data from 10x’s immunology-focused assays Use novel and existing methods to analyze immunological datasets Provide expertise and input into immunology product development Work with internal teams and external collaborators To be successful in this role, You will need: PhD or MS plus equivalent experience in a quantitative field (e.g.

biology, bioinformatics, computational/systems biology, physics, mathematics, computer science) Experience working on problems involving antigen receptor repertoires Ability to quickly conceive and implement custom computational methods and algorithms and apply them to large data sets Strong programming ability in a language such as Python or R Experience using computational methods to extract insight from large datasets Ability to work in a fast-paced and quickly changing environment Ability to communicate complex ideas with an interdisciplinary team Has experience with the analysis of NGS data Ability to work independently Additionally, it would be great to have: A deep intuition for the processes utilized by current NGS technologies Creative problem solver who obsesses over finding useful information in data Interest or experience in software engineering Hands on experience with single cell immune repertoire data A combination of analytical rigor with a healthy respect for the imperfections inherent in real-world data